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- Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent.
The process of gene silencing is important for the differentiation of many different types of cells. MedicineNet, Inc.
- Example sentence(s)
- Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. - biotech-info.net
by - The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? - The Thomson Corporation
by - In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. - ScienceDaily LLC
by Compare [close] - Spanish
- Biology (-tech,-chem,micro-)
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- Silenciamiento génico o genético
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- Silenciamiento génico es el mecanismo que regula la expresión genética, mediante el cual el ARN regula la expresión de ciertas regiones del ADN y define qué proteínas están presentes en la cédula. Own research - by Conchita Monedero
- Example sentence(s)
- El silenciamiento genético es un proceso sumamente importante en la mayoría de los organismos. Si una célula expresara todos y cada uno de sus genes sin una cierta regulación, el desorden generado en el interior de la misma podría conducir a una muerte celular inevitable. - ARN de interferencia y su importancia en
by Conchita Monedero - Análisis del silenciamiento génico en infecciones virales en plantas: proteínas virales supresoras en un sistema silenciado. En los últimos años se ha descrito un fenómeno de regulación de la expresión génica en eucariotas genéricamente conocido como silenciamiento por RNA o ribosilenciamiento. - Archivo Digital UPM
by Conchita Monedero - El mecanismo de silenciamiento génico transcripcional y postranscripcional está presente en la mayoría de los organismos eucariotas y fue descubierto a finales de la década de los 1980s. - Portales médicos.com
by Conchita Monedero - Related KudoZ question
Compare [close] - German
- Biology (-tech,-chem,micro-)
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- Gen-Silencing (Gen-Stilllegung)
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- Als Gen-Silencing (Gen-Stilllegung) wird ein Vorgang aus der Genetik bezeichnet, bei dem Gene aktiv abgeschaltet werden. Es handelt sich um einen (epigenetischen) Prozess der Genregulation. Wikipedia - by Harald Moelzer (medical-translator)
- Example sentence(s)
- Gene Silencing
Inaktivierung von Genen
Wenn Gene inaktiv werden, ohne dass sich der entsprechende DNA-Abschnitt verändert hat, spricht man von gene silencing. Dabei handelt es sich nicht um ein spezielles Phänomen in transgenen Pflanzen, sondern um natürliche Mechanismen, mit deren Hilfe Pilze, Tiere und Pflanzen ihre eigenen Gene regulieren. Sie können sich damit aber auch gegen fremdes Erbmaterial zur Wehr setzen. Das gene silencing basiert auf epigenetischen ("über" der DNA-Information gelegenen) Regulationsmechanismen und ist verwandt mit der RNA-Interferenz. - Biosicherheit.de
by Harald Moelzer (medical-translator) - Related KudoZ question
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