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          • disease-modifying anti-rheumatic drug (DMARD)
        • Additional fields of expertise
        • Definition(s)
          • Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the treatment of other disorders including connective tissue disease such as systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and Sjogren syndrome (SS), as well as in treatment of inflammatory myositis, vasculitis, uveitis, inflammatory bowel disease, and some types of cancers. National Center for Biotechnology Info.
        • Example sentence(s)
          • Hydroxychloroquine has been available since 1955 as an antimalarial drug. I have at least 6 patients at the pharmacy who have used hydroxychloroquine to manage their rheumatoid arthritis, lupus, and Crohn disease. If you were sitting in my pharmacology class, I’d tell you that it is an antimalarial used as a disease-modifying antirheumatic drug (DMARD). I would tell you it is a cheap drug with good efficacy for some and also that it is 1 of 2 DMARDs that are safe to use in patients with liver failure. You would also learn that it may cause deposition of the drug in the melanin layer of the cones in the retina, underscoring the need for annual eye exams. - MJH Life Sciences by
          • DMARDs Not Linked to Poor Outcomes in SARS-CoV-2 RA Patients - Rheumatology Network by
          • The analysis of performance measures for rheumatoid arthritis (RA) care have allowed to identify gaps in care that include suboptimal use of disease-modifying anti-rheumatic drugs (DMARDs), according to a study published in Arthritis Care & Research. - Rheumatology Advisor by
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    • Spanish
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        • Term
          • Fármaco antirreumático modificador de la enfermedad (FARME)
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          • Grupo de medicamentos empleados en el tratamiento de la artritis reumatoide cuya acción tiende a detener la actividad inflamatoria responsable del trastorno y puede mejorar el curso de la enfermedad. ConArtritis - by María Belén Di Memmo
        • Example sentence(s)
          • Los fármacos antirreumáticos modificadores de la enfermedad, o FARME, actúan para retrasar o detener la inflamación al suprimir la hiperactividad del sistema inmunológico. Esto ayuda a bajar la inflamación y la rigidez, disminuir o prevenir el daño articular y preservar la salud de los órganos vitales. - Arthritis Foundation by María Belén Di Memmo
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    • Polish
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          • leki przeciwreumatyczne modyfikujące przebieg choroby
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          • leki z tej grupy wykazują działanie przeciwzapalne i immunosupresyjne, ingerują w patomechanizm choroby i modyfikują jej naturalny przewlekle postępujący przebieg Termedia - by smerfetka1
        • Example sentence(s)
          • Leczenie skojarzone z metotreksatem czynnego RZS o umiarkowanym lub ciężkim nasileniu u dorosłych pacjentów niedostatecznie reagujących na inne leki przeciwreumatyczne modyfikujące przebieg choroby, w tym metotreksat. - ChPL certoliumab by smerfetka1
          • Niemniej poważne powikłania, jak chłoniaki, zakażenia, niewydolność krążenia, nie występowały częściej niż w grupie pacjentów stosujących leki przeciwreumatyczne modyfikujące przebieg choroby (DMARD – disease-modifying antirheumatic drug). - Medycyna po Dyplomie by smerfetka1
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    • Korean
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        • Term
          • 질병 조절 항류마티스제
        • Additional fields of expertise
        • Definition(s)
          • 메토트렉세이트, 히드록시클로로퀸, 레프루노미드, 설파살라진과 같은 DMARD는 류마티스 관절염 진행을 늦추고, 거의 모든 류마티스 관절염 환자들에 투여합니다. 의사들은 일반적으로 류마티스 관절염을 진단하는 즉시 이 약물들을 처방합니다. 약효가 나타나는 데 몇 주 또는 몇 달이 소요됩니다. 증상이 없거나 경증인 경우에도 질환이 진행하므로, NSAID로 통증이 감소한 경우에도 의사가 DMARD를 처방할 가능성이 높을 것입니다. MSD 매뉴얼 - by Zoe Lee
        • Example sentence(s)
          • 국내에는 약 50만명의 류마티스 관절염 환자가 있다. 현재 비스테로이드성 항염증제, 질병 조절 항류마티스제, 코르티코스테로이드, 면역억제제 등의 약물로 증상을 완화하거나 염증을 치료하고 있다. - 메디컬투데이 by Zoe Lee
          • 현재 비스테로이드성 항염증제(NSAID), 질병 조절 항류마티스제(DMARD), 코르티코스테로이드, 면역억제제 등의 약물로 증상을 완화하거나 염증을 치료하고 있지만 일시적 환화 작용에 그칠뿐 완벽한 치료제는 없는 상황이다. - 중도일보 by Zoe Lee
          • 이번 학회에서 발표된 JAK억제제 연구에 따르면 페피시티닙의 경우 DMARDs(질병조절 항류마티스제)로 효과를 얻을 수 없는 환자 500여명을 대상으로 한 연구에서 효과가 입증됐다. 필고티닙 효과도 24주 연구에서 입증됐으며, 바리시티닙은 조기사용에, 토파시티닙은 생물학적제제 사용 여부와 무관하게 매우 효과적으로 확인됐다. - 메디칼트리뷴 by Zoe Lee
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