Glossary entry (derived from question below)
English term or phrase:
gene silencing
Slovak translation:
potlačenie transkripcie génov
Feb 9, 2010 13:59
14 yrs ago
English term
gene silencing
GBK
English to Slovak
Science
Biology (-tech,-chem,micro-)
Definition from
MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent.
The process of gene silencing is important for the differentiation of many different types of cells.
Example sentences:
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
Proposed translations
(Slovak)
4 +2 | potlačenie transkripcie génov |
Dagmar Turčanová
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4 | tlmenie génov, tlmenie aktivity génov |
Igor Liba
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Change log
Feb 9, 2010 13:01: changed "Kudoz queue" from "In queue" to "Public"
Feb 9, 2010 13:59: changed "Stage" from "Preparation" to "Submission"
Feb 12, 2010 15:08: changed "Stage" from "Submission" to "Selection"
Mar 11, 2010 15:54: changed "Stage" from "Selection" to "Completion"
Proposed translations
+2
28 mins
Selected
potlačenie transkripcie génov
Uvádza sa aj „tíšenie génov“, „tlmenie génov“, „inhibícia transkripcie/translácie“
Definition from
own experience or research:
Inhibícia transkripcie/translácie špecifických génov
Example sentences:
Zahrňuje potlačenie transkripcie génov (gene silencing) v závislosti na bunkovej diferenciácií (Jihočeská univerzita)
4 KudoZ points awarded for this answer.
21 mins
tlmenie génov, tlmenie aktivity génov
Definition from
Rezortná úloha výskumu a vývoja MP S:
Na reguláciu expresie myostatínu králika plánujeme použiť RNA interferenciu (RNAi) čo je evolučne vysoko konzervovaný proces postranskripčného tlmenia génov (PTGS) indukovaný dvojreťazcovou RNA (dsRNA).
Example sentences:
Následne výskumy zázvorového extraktu postúpili do fázy zisťovania inhibície – tlmenia niekoľkých génov zúčastňujúcich sa zápalovej reakcie. (Nutraceutika)
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