Glossary entry

English term or phrase:

antibodies not RA

Spanish translation:

anticuerpos no AR

Added to glossary by rhandler
Oct 13, 2007 16:12
16 yrs ago
1 viewer *
English term

antibodies not RA

English to Spanish Medical Genetics
How do you interpret this sentence?

Recent data demonstrated that the SE is a risk factor for CCP antibodies not RA

SE: Secuencia de aminoácidos
CCP antibodies: anticuerpos CCP, anticuerpos péptidos citrulinados cíclicos
RA: artritis reumatoidea

Thanks for helping.
Blanca
Change log

Oct 14, 2007 19:13: rhandler changed "Edited KOG entry" from "<a href="/profile/2751">Blanca Amoroso's</a> old entry - "antibodies not RA"" to ""anticuerpos no AR""

Discussion

Blanca Amoroso (asker) Oct 13, 2007:
Comments You're right liz. SE should be Shared Epitope. The confusion comes from the source text: "RA associated alleles share a common amino acid sequence (SE) in antigen binding cleft of the DR molecule".

"...Is this text written by a native English speaker? It's just that all the refs on google that I find have "anti-CCP antibodies", rather than your version.."

The source text reads:"Treatment- Early administration of DMARD therapy in view of severity of symptoms and the presence of CCP antibodies"
"Diagnostic Tests in RA: Anti-CCP Antibodies"...
liz askew Oct 13, 2007:
Does this make your sentence clearer?
van der Helm-van Mil AH, Verpoort KN, Breedveld FC, Huizinga TW, Toes RE, de Vries RR. The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies andare not an independent risk factor for development of rheumatoid arthritis. Arthritis Rheum 2006;54:1117-1121
liz askew Oct 13, 2007:
Is this text written by a native English speaker? It's just that all the refs on google that I find have "anti-CCP antibodies", rather than your version..
liz askew Oct 13, 2007:
ARJ Research article The PTPN22 1858C/T polymorphism is ...HLA-shared epitope (SE) alleles and smoking have also recently been shown to act synergistically as risk factors, but only in anti-CCP antibody-positive ...
www.biomedcentral.com/content/download/xml/ar2214.xml - 94k - Cached - Similar pages

liz askew Oct 13, 2007:
Ver: 2. Los acoplamientos genéticos con artritis reumatoide identificaron
Aunque la causa exacta de la artritis reumatoide (RA) no se sabe, ha llegado a ser de aumento claramente que esta enfermedad tiene orígenes genéticos y ambientales. En diciembre de 2005, un equipo internacional de los científicos lanzó resultados de su estudio en el diario americano de la genética humana que examinaban varios genes que pueden aumentar el riesgo de una persona de desarrollar el RA. Conocían a la gente con un grupo específico de genes llamados HLA-DRB1 (también conocido como el epitope compartido) ya para tener un riesgo creciente de desarrollar el RA. Ahora se ha determinado que por lo menos un otro gene aumenta la probabilidad de desarrollar el RA, y las conexiones posibles fueron encontradas para dos más.
liz askew Oct 13, 2007:
Are you sure "SE" = aminoacid sequency, as I have found that "SE" = shared Epitope (alleles):
The HLA-DRB1 shared epitope alleles are primarily a risk factor ...OBJECTIVE: The shared epitope (SE)-containing HLA-DRB1 alleles represent the most significant genetic risk factor for rheumatoid arthritis (RA). ...
arthritis-research.com/pubmed/16572446 - Similar pages

Proposed translations

+1
14 mins
Selected

anticuerpos no AR

Vea este ejemplo:

[PDF] Page 1 D I A S T A T ™ Anti-CCP Anti-CCP Anti-PCC Anti-CCP Anti ...
File Format: PDF/Adobe Acrobat - View as HTML
Durante varios años, se ha reconocido que los anticuerpos al ..... Especificidad Clínica en Estadíos de la Enfermedad No AR y Asintomáticos ...
www.inmunomex.com/pdf/DIASTAT.pdf
Peer comment(s):

agree Nora Bellettieri
6 hrs
Gracias, Nora!
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Ésta es la respuesta correcta, necesitaba que alguien me corroborara, no quería ponerlo tan literal. Para que entiendan, "anti-CCP+ non-RA" se refiere a la presencia de anticuerpos anti-péptidos citrulinados cíclicos en la enfermedad inflamatoria no clasificada como Artritis Reumatoidea según los criterios del Colegio Norteamericano de Reumatología. "
26 mins

ver abajo p.f.

Well, I think this could be the meaning of your sentence and is much clearer:

And if someone else gets the points for translating into Spanish, I will be somewhat peeved! :)

van der Helm-van Mil AH, Verpoort KN, Breedveld FC, Huizinga TW, Toes RE, de Vries RR. The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies andare not an independent risk factor for development of rheumatoid arthritis. Arthritis Rheum 2006;54:1117-1121
Something went wrong...
+1
22 hrs

los anticuerpos CCP no artritis reumatoidea

Los avances de tecnologia son tan rapidos y dominates que se esta criado otro idioma, practicamente separado de todos. Esto, con la idealogia que hoy en dia tenemos una economia global, nos lleva a un idioma nuevo que se esta desarollano en todo momento.
Example sentence:

Recentes datos han demonstratdo que SSE es el factor de riesgo de los anticuerpos CCP, no artritis reumatoidea

Peer comment(s):

agree liz askew : This is clearer, otherwise it means RA antibodies, and the English doesn't mean this.//Personally, I think the English is poorly-expressed, rather than it being matter of progress in technology. English is capable of describing anything properly.
18 hrs
Something went wrong...
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