Glossary entry (derived from question below)
English term or phrase:
histology yield
English answer:
tissue acquisition for histological analysis
Added to glossary by
Daniel Grigoras
Jun 2, 2014 12:29
10 yrs ago
1 viewer *
English term
histology yield
English
Medical
Medical (general)
"Market shift to histology yield could lead to new treatment modalities"
The above phrase is taken from the description of a medical device.
The above phrase is taken from the description of a medical device.
Responses
+1
4 hrs
Selected
tissue acquisition for histological analysis
There is material online about histology yield, often compared with cytology yield, in relation to different types and sizes of biopsy needles. It seems clear that the point at issue is how much useful tissue is extracted in the biopsy for one type of analysis versus another, bearing in mind that cytology is to do with loose cells whereas histology is to do with miscroscopic anatomy of tissues, so presumably a different kind of material is required depending on which it is for.
Here, for example, is an article entitled "Prospective pilot evaluation of a new needle prototype for endoscopic ultrasonography-guided fine-needle aspiration: comparison of cytology and histology yield". The abstract makes it clear that "yield" means material extracted with a needle in a biopsy:
"In each patient we aimed to make two needle passes, and if the material acquired appeared insufficient macroscopically (no in-room cytopathology was available), further passes were done. The material was sent for cytological and histological assessment."
http://www.ncbi.nlm.nih.gov/pubmed/18334879
But the most useful document I've found is this one, on types of needles for this purpose:
"In recent studies, Kenneth Chang, MD, Executive Director, H. H. Chao Comprehensive Digestive Disease Center (University of California-Irvine), found that a new 25 gage biopsy needle developed by Cook Medical combined the attributes of both FNA and FNB, and delivered a single-pass diagnosis of 88% in suspected tumors of the pancreas when pathologists examined both the histological and cytological yield obtained.
“We haven’t done a head-to-head comparison yet,” says Dr. Chang, “but I think we’d be able to say that this 25 gage needle is as good if not better than the standard 25 when comparing cytology yields [...]
“I was already familiar with the 19 and 22 gage ProCore needles,” Dr. Chang continues. “But eventually we asked a simple question: ‘What would happen if you made a 25 gage EUS needle in the same configuration?’ The initial thought was, of course, you’re going to have a worse yield. Because you’re looking at a core needle that is smaller; therefore, the yield should decrease. But, pushing that assumption aside, we knew that if we didn’t try we would never know for sure. So, based on initial discussions, Cook Medical decided to manufacture a limited number of 25 gage needles. And, so far, we feel that it outperforms the 19 gage and the 22 gage for tissue acquisition."
https://www.cookmedical.com/documents/42434/0/The_Channel-is...
You need to remember that the higher the number, the smaller (thinner) the needle.
So yield, clearly, means tissue acquisition, and histology yield is acquisition of suitable tissue for histology as opposed to cytology. The "market shift to histology yield" may means that the market in medical equipment is placing greater emphasis on needles with a good histology yield as opposed to cytology yield.
Here, for example, is an article entitled "Prospective pilot evaluation of a new needle prototype for endoscopic ultrasonography-guided fine-needle aspiration: comparison of cytology and histology yield". The abstract makes it clear that "yield" means material extracted with a needle in a biopsy:
"In each patient we aimed to make two needle passes, and if the material acquired appeared insufficient macroscopically (no in-room cytopathology was available), further passes were done. The material was sent for cytological and histological assessment."
http://www.ncbi.nlm.nih.gov/pubmed/18334879
But the most useful document I've found is this one, on types of needles for this purpose:
"In recent studies, Kenneth Chang, MD, Executive Director, H. H. Chao Comprehensive Digestive Disease Center (University of California-Irvine), found that a new 25 gage biopsy needle developed by Cook Medical combined the attributes of both FNA and FNB, and delivered a single-pass diagnosis of 88% in suspected tumors of the pancreas when pathologists examined both the histological and cytological yield obtained.
“We haven’t done a head-to-head comparison yet,” says Dr. Chang, “but I think we’d be able to say that this 25 gage needle is as good if not better than the standard 25 when comparing cytology yields [...]
“I was already familiar with the 19 and 22 gage ProCore needles,” Dr. Chang continues. “But eventually we asked a simple question: ‘What would happen if you made a 25 gage EUS needle in the same configuration?’ The initial thought was, of course, you’re going to have a worse yield. Because you’re looking at a core needle that is smaller; therefore, the yield should decrease. But, pushing that assumption aside, we knew that if we didn’t try we would never know for sure. So, based on initial discussions, Cook Medical decided to manufacture a limited number of 25 gage needles. And, so far, we feel that it outperforms the 19 gage and the 22 gage for tissue acquisition."
https://www.cookmedical.com/documents/42434/0/The_Channel-is...
You need to remember that the higher the number, the smaller (thinner) the needle.
So yield, clearly, means tissue acquisition, and histology yield is acquisition of suitable tissue for histology as opposed to cytology. The "market shift to histology yield" may means that the market in medical equipment is placing greater emphasis on needles with a good histology yield as opposed to cytology yield.
4 KudoZ points awarded for this answer.
Comment: "Thanks!"
4 hrs
rendimiento histológico
The correct term in English appears to be "histological yield". I cannot find its definition but it seems to be a type of diagnostical technique for gastrointestinal diseases.
There are several instances of "rendimiento histológico" in medical papers written in Spanish:
Revista Española de Enfermedades Digestivas:
http://scielo.isciii.es/scielo.php?pid=S1130-010820100005000...
"El rendimiento histológico de las biopsias endoscópicas convencionales se encuentra alrededor del 25%."
Endoscopia. Módulo II, Enfermedades gastroduodenales:
http://zl.elsevier.es/es/revista/endoscopia-335/modulo-ii-en...
"Asimismo, señalaron que esta técnica puede ser una alternativa confiable a la biopsia por aspiración guiada por USE que puede mejorar el rendimiento histológico."
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Note added at 7 horas (2014-06-02 19:56:32 GMT)
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Sorry, I had mistaken this for an English-Spanish query. However, as I said, the term "histological yield" appears to be more frequent than "histology yield", maybe the definition is easier to find if you search for such term.
There are several instances of "rendimiento histológico" in medical papers written in Spanish:
Revista Española de Enfermedades Digestivas:
http://scielo.isciii.es/scielo.php?pid=S1130-010820100005000...
"El rendimiento histológico de las biopsias endoscópicas convencionales se encuentra alrededor del 25%."
Endoscopia. Módulo II, Enfermedades gastroduodenales:
http://zl.elsevier.es/es/revista/endoscopia-335/modulo-ii-en...
"Asimismo, señalaron que esta técnica puede ser una alternativa confiable a la biopsia por aspiración guiada por USE que puede mejorar el rendimiento histológico."
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Note added at 7 horas (2014-06-02 19:56:32 GMT)
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Sorry, I had mistaken this for an English-Spanish query. However, as I said, the term "histological yield" appears to be more frequent than "histology yield", maybe the definition is easier to find if you search for such term.
Peer comment(s):
neutral |
liz askew
: this is an English-English query
2 hrs
|
Sorry, I hadn't noticed! Thank you Liz!
|
Reference comments
11 mins
Reference:
see
http://www.medilexicon.com/medicaldictionary.php?t=100304
histological sampling involves taking samples of cells
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Note added at 12 mins (2014-06-02 12:42:16 GMT)
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having said that I can find no examples of your phrase on line
you need to provide a few more sentences in English for further context
Histopathologic Diagnosis of Fungal Infections in the 21st ...
www.ncbi.nlm.nih.gov/...
National Center for Biotechnology Information
by J Guarner - 2011 - Cited by 48 - Related articles
Thus, a shift in the mycoses encountered in the health care setting has occurred. ... obtained and the architectural distortion produced by these new procedures. .... these results to guide treatment, particularly because B. dermatitidis can take up to ... The diagnostic yield of histopathology will depend on the expertise present ...
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Note added at 15 mins (2014-06-02 12:45:05 GMT)
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http://medical-dictionary.thefreedictionary.com/Diagnostic Y...
diagnostic yield
The likelihood that a test or procedure will provide the information needed to establish a diagnosis. See Clinical decision making.
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Note added at 24 mins (2014-06-02 12:53:59 GMT)
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histology yield =
number of cells harvested from histology sampling
this is the best I can do
histological sampling involves taking samples of cells
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Note added at 12 mins (2014-06-02 12:42:16 GMT)
--------------------------------------------------
having said that I can find no examples of your phrase on line
you need to provide a few more sentences in English for further context
Histopathologic Diagnosis of Fungal Infections in the 21st ...
www.ncbi.nlm.nih.gov/...
National Center for Biotechnology Information
by J Guarner - 2011 - Cited by 48 - Related articles
Thus, a shift in the mycoses encountered in the health care setting has occurred. ... obtained and the architectural distortion produced by these new procedures. .... these results to guide treatment, particularly because B. dermatitidis can take up to ... The diagnostic yield of histopathology will depend on the expertise present ...
--------------------------------------------------
Note added at 15 mins (2014-06-02 12:45:05 GMT)
--------------------------------------------------
http://medical-dictionary.thefreedictionary.com/Diagnostic Y...
diagnostic yield
The likelihood that a test or procedure will provide the information needed to establish a diagnosis. See Clinical decision making.
--------------------------------------------------
Note added at 24 mins (2014-06-02 12:53:59 GMT)
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histology yield =
number of cells harvested from histology sampling
this is the best I can do
Note from asker:
Here's another phrase: "Key Benefits: Obtains histology samples (tissue) vs. cytology samples (cells)"; I have translated it with "sampling", but someone else proposed "testing". |
Discussion
Good luck!