English to Russian Science Mathematics & Statistics

This approach identified genes which had a high fold-change in expression compared to sham: two (Hmoxl and Srxnl) in the RNE, eight (including Cyplal and Prr5l) in the bronchi, and five (including Fam46b and Nrcam) in the parenchyma; the expression of most of these genes were also seen in the 3R4F compared with the sham group in the respective tissues (Supplemental Table 10).
For a more detailed description, see Supplemental Results S2.3.
GSEA was used to detect biological activity unique to pMRTP exposure.
GSEA provides enhanced sensitivity and is more comprehensive than *relaxing the statistical threshold* because it focuses on groups of genes (so-called gene sets) that share common biological functions (Subramanian et al., 2005).
Under the applied threshold (gene set with FDR