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English to Swedish: Swedish translation sample General field: Other Detailed field: Medical: Health Care
Source text - English Clinical trials suggest that the selective COX-2 inhibitor class of drugs may be associated with a risk of thrombotic events (especially myocardial infarction (MI) and stroke), relative to placebo and some NSAIDs. As the cardiovascular risks of xxxTablets may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically, especially in patients with osteoarthritis (see sections 4.2, 4.3, 4.8 and 5.1).
Patients with significant risk factors for cardiovascular events (e.g. hypertension, hyperlipidaemia, diabetes mellitus, smoking) should only be treated with xxx Tablets after careful consideration (see section 5.1).
COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect. Therefore antiplatelet therapies should not be discontinued (see sections above, 4.5 and 5.1.).
Renal effects
Renal prostaglandins may play a compensatory role in the maintenance of renal perfusion. Therefore, under conditions of compromised renal perfusion, administration of xxx Tablets may cause a reduction in prostaglandin formation and, secondarily, in renal blood flow, and thereby impair renal function. Patients at greatest risk of this response are those with pre-existing significantly impaired renal function, uncompensated heart failure, or cirrhosis. Monitoring of renal function in such patients should be considered.
Translation - Swedish Kliniska studier tyder på att den selektiva COX-2-hämmarklassen av läkemedel kan vara associerad med risk för trombotiska händelser (särskilt hjärtinfarkt (MI) och apolexi) i förhållande till placebo och vissa NSAIDs.Eftersom kardiovaskulära risker för xxx-tabletterkan öka med dos och exponeringstid, ska den kortaste varaktigheten och den lägsta effektiva dagliga dosen användas.Patientens behov av symtomatisk lindring och reaktion på behandlingen bör regelbundet omvärderas, särskilt hos patienter med artros (se avsnitt 4.2, 4.3, 4.8 och 5.1).
Patienter med betydande risk faktorer för kardiovaskulära händelser (t.ex.hypertoni, hyperlipidaemia, diabetes mellitus, rökning) ska endast behandlas med xxx-tabletter efter noggrantövervägande (se avsnitt 5.1).
COX-2 selektiva hämmare är inte ett substitut föracetylsalicylsyra för profylax av kardiovaskulära trombo-emboliska sjukdomar på grund av deras brist av antiplatelet effekt. Därför bör antiplateletterapierinte avbrytas (se avsnitten ovan, 4.5 och 5.1.).
Renala effekter
Renala prostaglandiner kan spela en kompensationsroll vid upprätthållandet av renal perfusion.Därför kan administrering av xxx-tabletter under förhållanden av komprometterad njurperfusion orsaka en minskning av prostaglandinbildningen och, sekundärt, vid renalt blodflöde och därigenom försämra njurfunktionen.Patienter med största risken för denna reaktionär de med en redanexisterande signifikant nedsatt njurfunktion, okompenserad hjärtsvikt eller cirros.Övervakning av njurfunktionen hos sådana patienter bör övervägas.
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Years of experience: 27. Registered at ProZ.com: Jun 2017. Became a member: Jun 2017.
My name is Julia Nelson, I a full-time bilingual German/Danish translator with excellent knowledge of English and Spanish.
I have 18 years of translation experience in different fields such as Legal, Marketing, Technology, Pharma, Media, Communications, Literature, Games, Food, Traveling and many more.
My rates: $0,05 per word for
translation; $0,025 - for proofreading.
I am available 7 days a week and respond ASAP via email.
Keywords: German translation, Danish translation, Swedish translation, Norwegian translation, Bulgarian translation, Czech translation, Latvian translation, Portuguese translation, Polish translation, Romanian translation. See more.German translation, Danish translation, Swedish translation, Norwegian translation, Bulgarian translation, Czech translation, Latvian translation, Portuguese translation, Polish translation, Romanian translation, Serbian translation, Slovenian translation, technical translation, medical translation, Russian translation, voiceover. See less.